Introduction to glycoprotein synthesis
and glycosylation services
KH Neochem uses glycans to provide glycoprotein synthesis and glycosylation services. We can support research and development of biosimilars and ADCs (antibody-drug conjugates). Glycosylation technologies make it possible to link glycans to Asn or Cys residues in peptides and proteins.
We provide these services jointly with our partner, GlyTech, Inc.
Glycosylation by chemical reaction
Our principal glycosylation technologies make it possible to link glycans to Asn or Cys residues in peptides and proteins.
Solid phase synthesis of peptides with glycan linked to Asn
Glycosylation to Cys
Glycoprotein synthesis
We provide glycosylated biopharmaceuticals that are produced through a wide variety of synthetic technologies utilizing complete chemical synthesis pathways, semi-chemical synthesis pathways, and expressed protein glycosylation pathways, depending on the glycoprotein structure.
Glycoprotein design/glycoengineering
Everything from glycosylation positions to glycan structures can be flexibly designed with the “rational drug design” approach, which makes it possible to create novel biopharmaceuticals and optimize the properties and efficacy of therapeutics.